A New Bio-marker Test for DCIS = Peace of Mind for Thousands of Women

peace-of-mindIf you are one of the 60,000 + women diagnosed with DCIS this year, you now have a way to gain more peace of mind about what to think and do about it.

A company called PreludeDx has scientifically validated a bio-marker test which evaluates a woman’s breast tissue sample and provides a “personalized” risk assessment based on her unique biology.

The test is called DCISionRT.

Had this test been available in 2010 when I was diagnosed with DCIS, I would have learned extremely valuable information that would have given me, my family AND my team of physicians great confidence in MY decisions.

Instead I found myself in a very lonely place. I was continually scared and pressured by physicians as well as women in online DCIS forums to succumb to aggressive cancer treatments — procedures and drugs that felt more toxic, scary and harmful than the actual DCIS diagnosis.

Fast forward 8.5 years.

The PreludeDx team discovered my story and arranged to test my original DCIS biopsy tissue from 2010.


According to Troy Bremer, co-founder and Chief Scientific Officer at PreludeDx, “You have very clean biology for DCIS.”

He personally went over the results of my DCISionRT test with me which you can see below.

My Score was less than 1 out of 10 (0.8 / 10), with 9% risk of total 10-year recurrence and no expected benefit from radiation therapy.

Prelued Risk Results_DonnaIs this the picture of a woman in need of a mastectomy or weeks of daily radiation?

Is this someone who deserved to be told by a breast cancer physician, “Don’t be stupid Donna… at least do 3 weeks of radiation.

Unfortunately, DCISionRT was not available in 2010.

While I am thankful I had my strong intuition and a number of articles and studies on suspected over-diagnosis and over-treatment of DCIS, I now have the scientific proof that I  made the right choices and said NO to weeks of radiation or mastectomy.

Hopefully thousands of women today can be spared the frightening feeling that comes with uncertainty and can instead have more personalized information to support their decisions for active surveillance if they are low-risk rather than be continually pressured towards a one-size-fits-all highly aggressive treatment protocol.

In the past, studies have shown 97% of women end up doing aggressive treatments for DCIS. confusedLack of knowledge about the biological nature of DCIS coupled with fear and anxiety have been strong motivators.

Not only does DCISionRT give a woman and her family tremendous peace of mind, it can provide physicians the scientific evidence to feel more confident in supporting both someone like me — with a low-risk DCIS — to someone who is at a more elevated risk.

I believe DCISionRT will help shift the paradigm away from needless emotional trauma, (worry, overwhelm, confusion, uncertainty, intimidation and fear),  as well as help stop the problem known as “over-treatment” of DCIS.

I hope all health-care providers and organizations concerned with “early detection” of breast cancer embrace this important test.

When it comes to DCIS, there is no price tag for peace of mind.


If your doctor is unaware or unsupportive of DCISionRT, contact PreludeDx at this link.

I recently enjoyed a lab tour and meeting with the PreludeDx team at their office in Laguna, California.

Thank you Prelude Dx for advancing the science of DCIS and for treating me like a VIP!

To learn more about DCISionRT, click here.

About Donna Pinto

I am originally from New Jersey and moved to Los Angeles with my family at age 12. After graduating from San Diego State University with a BA in Journalism, I had a short-stint in magazine advertising sales before landing my "dream job" with Club Med. For two years I worked at resorts in Mexico, The Bahamas, The Dominican Republic and Colorado. My husband Glenn & I met in Ixtapa, Mexico and we embarked on a two year honeymoon around the world. This was also a research project for a book we wrote called "When The Travel Bug Bites: Creative Ways to Earn, Save and Stay Abroad." I am also the author of a quote book for new graduates -- "Cheatnotes on Life: Lessons From The Classroom of Life." In 1997, we settled in San Diego and I was blessed to work part-time from home for non-profit organizations while raising our two boys. In 2010, a DCIS diagnosis changed my life. DCIS 411 is the culmination of my on-going journey and discoveries.
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6 Responses to A New Bio-marker Test for DCIS = Peace of Mind for Thousands of Women

  1. Amy Sarringhaus says:

    Such good news! I did the Oncotype Dx test for DCIS and that showed a low chance of reoccurrence for me. I did do a week of twice daily radiation, but declined Tamoxifen therapy.
    Thank you, Donna, for all the research you have done for those of us diagnosed with DCIS.


  2. Judy says:

    Can this test be used for LCIS and FLCIS? I have both.


  3. Joya Shepard says:

    Thanks for posting this. I just read it again after getting my results from the Prelude test. I had a lumpectomy on July 21st. My score was 0.8 with a 7% risk of DCIS recurrence after lumpectomy and the same for surgery and radiation. It was 3% for invasive with or without radiation. No radiation or endocrine treatment for me. However, I am meeting with a Naturopathic Oncologist for strategies to address estrogen and lifestyle changes.


  4. Éva says:

    Is this test is available only in the USA pls? I am from Europe.


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